Diaphragm Valves

Diaphragm valves are designed to regulate the flow of liquids and gases by using a flexible diaphragm to create a secure seal. These valves are ideal for applications where the transported media is corrosive, abrasive, or requires sanitary handling. Their simple yet effective design minimizes the risk of contamination, making them widely used in industries such as chemical processing, pharmaceuticals, food and beverage, and water treatment.


Centro offers a comprehensive selection of diaphragm valves in manual and pneumatic actuated designs to suit various operational needs. Whether you require precise hand-operated flow control or an automated valve for high-efficiency processing, we have the right solution.

Types of Diaphragm Valves We Offer

  • Manual Diaphragm Valves – Hand-operated for precise control in low-pressure systems
  • Pneumatic Actuated Diaphragm Valves – Use compressed air for automated on/off operation
  • Weir-Type Diaphragm Valves – Provide excellent sealing for corrosive and particulate-laden fluids
  • Straight-Through Diaphragm Valves – Offer minimal flow resistance for high-purity applications
  • Sanitary Diaphragm Valves – Designed for hygienic industries, including food, beverage, and pharmaceuticals

Why Choose Diaphragm Valves from Centro?

  • Superior sealing performance for corrosive, abrasive, and sanitary applications
  • Available in a variety of materials, including stainless steel, plastic, and lined options
  • Suitable for industries such as chemical processing, pharmaceuticals, biotechnology, and water treatment
  • Sourced from trusted manufacturers to ensure durability, reliability, and compliance with industry standards


Centro provides high-quality diaphragm valves designed for long-lasting performance. Browse our selection and order online today, or contact our team for expert assistance in selecting the right valve for your application.

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AQ Matic/Aquamatic and Control Valves 4500271 - V427,3.00,NPT,CI,NO/SAO,BLU

$770.71$934.46

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500272 - V429,6.00,ASTM,CI,NO,BLUE

$5,547.23$6,725.87

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500273 - V427,3.00,BSP,CI,NO

$687.49$833.56

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500274 - V424,1.50,NPT,CI,NO,

$263.65$319.66

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500275 - K521,1.00,PLS,NO,FKM,DT #2

$199.64$242.05

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500276 - K521,1.00,PLS,NO,FKM,DT #2

$195.89$237.51

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500287 - V421,1.00,NPT,CI,NO/SAO

$238.41$289.06

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500289 - V465,2.00,NPT,SS,NC,VIT

$1,004.36$1,217.76

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500290 - V427,3.00,NPT,CI,NO,EC

$965.60$1,170.76

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500291 - V425,2.00,NPT,CI,NO/LS/SAO

$552.48$669.86

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500292 - V426,2.50,NPT,CI,NO/LS,BLUE

$507.65$615.51

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500296 - K5524,1.50,PLS,SC60,CSTM,SILC

$966.78$1,172.19

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500297 - K535,2.00,PLS,NO/SC100,CSTM S

$1,545.84$1,874.28

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500298 - K535,2.00,PLS,NO/CSTM,SF

$873.08$1,058.58

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500302 - V421,0.75,NPT,CI,NO,

$197.93$239.98

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500303 - V426,2.00,NPT,CI,NO/LS,

$571.49$692.91

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500317 - V428,4.00,ASTM,CI,NO/LS

$1,656.67$2,008.66

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500319 - V427,3.00,ASTM,CI,NO,PAINT BL

$790.89$958.93

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500320 - V461,1.00,NPT,SS,NC/SAC,BUNA-

$665.59$807.01

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500326 - V424,1.50,NPT,BRS,NO/SAC,EO

$887.26$1,075.77

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500328 - K535,2.00,PLS,NO,EC,SOLENOID

$1,172.75$1,421.92

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500331 - VAV5,2.00,NPT,CI,NO/SAO

$497.06$602.67

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500332 - V427,3.00,ASTM,CI,NO/LS/SAO

$919.90$1,115.35

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500334 - V427,3.00,NPT,CI,NO,DT#12,B

$686.37$832.20

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500271 - V427,3.00,NPT,CI,NO/SAO,BLU

$770.71$934.46

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500272 - V429,6.00,ASTM,CI,NO,BLUE

$5,547.23$6,725.87

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500273 - V427,3.00,BSP,CI,NO

$687.49$833.56

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500274 - V424,1.50,NPT,CI,NO,

$263.65$319.66

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500275 - K521,1.00,PLS,NO,FKM,DT #2

$199.64$242.05

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500276 - K521,1.00,PLS,NO,FKM,DT #2

$195.89$237.51

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500287 - V421,1.00,NPT,CI,NO/SAO

$238.41$289.06

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500289 - V465,2.00,NPT,SS,NC,VIT

$1,004.36$1,217.76

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500290 - V427,3.00,NPT,CI,NO,EC

$965.60$1,170.76

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500291 - V425,2.00,NPT,CI,NO/LS/SAO

$552.48$669.86

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500292 - V426,2.50,NPT,CI,NO/LS,BLUE

$507.65$615.51

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500296 - K5524,1.50,PLS,SC60,CSTM,SILC

$966.78$1,172.19

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500297 - K535,2.00,PLS,NO/SC100,CSTM S

$1,545.84$1,874.28

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500298 - K535,2.00,PLS,NO/CSTM,SF

$873.08$1,058.58

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500302 - V421,0.75,NPT,CI,NO,

$197.93$239.98

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500303 - V426,2.00,NPT,CI,NO/LS,

$571.49$692.91

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500317 - V428,4.00,ASTM,CI,NO/LS

$1,656.67$2,008.66

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500319 - V427,3.00,ASTM,CI,NO,PAINT BL

$790.89$958.93

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500320 - V461,1.00,NPT,SS,NC/SAC,BUNA-

$665.59$807.01

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500326 - V424,1.50,NPT,BRS,NO/SAC,EO

$887.26$1,075.77

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500328 - K535,2.00,PLS,NO,EC,SOLENOID

$1,172.75$1,421.92

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500331 - VAV5,2.00,NPT,CI,NO/SAO

$497.06$602.67

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500332 - V427,3.00,ASTM,CI,NO/LS/SAO

$919.90$1,115.35

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500334 - V427,3.00,NPT,CI,NO,DT#12,B

$686.37$832.20

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

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