Diaphragm Valves

Diaphragm valves are designed to regulate the flow of liquids and gases by using a flexible diaphragm to create a secure seal. These valves are ideal for applications where the transported media is corrosive, abrasive, or requires sanitary handling. Their simple yet effective design minimizes the risk of contamination, making them widely used in industries such as chemical processing, pharmaceuticals, food and beverage, and water treatment.


Centro offers a comprehensive selection of diaphragm valves in manual and pneumatic actuated designs to suit various operational needs. Whether you require precise hand-operated flow control or an automated valve for high-efficiency processing, we have the right solution.

Types of Diaphragm Valves We Offer

  • Manual Diaphragm Valves – Hand-operated for precise control in low-pressure systems
  • Pneumatic Actuated Diaphragm Valves – Use compressed air for automated on/off operation
  • Weir-Type Diaphragm Valves – Provide excellent sealing for corrosive and particulate-laden fluids
  • Straight-Through Diaphragm Valves – Offer minimal flow resistance for high-purity applications
  • Sanitary Diaphragm Valves – Designed for hygienic industries, including food, beverage, and pharmaceuticals

Why Choose Diaphragm Valves from Centro?

  • Superior sealing performance for corrosive, abrasive, and sanitary applications
  • Available in a variety of materials, including stainless steel, plastic, and lined options
  • Suitable for industries such as chemical processing, pharmaceuticals, biotechnology, and water treatment
  • Sourced from trusted manufacturers to ensure durability, reliability, and compliance with industry standards


Centro provides high-quality diaphragm valves designed for long-lasting performance. Browse our selection and order online today, or contact our team for expert assistance in selecting the right valve for your application.

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AQ Matic/Aquamatic and Control Valves 4500422 - V421,1.00,NPT,CI,NC,BLUE

$214.48$260.05

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500423 - K535,2.00,PLS,XNC/LS/PI/SAC

$1,044.77$1,266.75

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500424 - K535,2.00,PLS,NO/SC100 DT 1,

$1,532.70$1,858.35

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500425 - V461,1.00,NPT,SS,NO/SAO,BUNA

$601.99$729.89

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500426 - V427,3.00,NPT,CI,NC,

$695.10$842.78

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500438 - V424,1.25,NPT,CI,NC/SAC,

$335.42$406.68

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500439 - K535,2.00,PLS,NO, DT BOSS #1

$843.26$1,022.43

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500440 - V428,4.00,ASTM,CI,NO/LS/SAO,B

$1,439.66$1,745.54

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500441 - V428,4.00,ASTM,CI,NC/LS,BLUE

$1,452.53$1,761.15

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500443 - K531,1.00,PLS,NO,EO,STD,DT #

$611.30$741.18

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500445 - V424,1.50,NPT,CI,NC/LS,

$308.08$373.53

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500446 - V424,1.50,NPT,CI,NO/PI/SAO

$400.24$485.28

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500447 - V426,2.50,NPT,CI,NC,HI TEMP,E

$500.40$606.72

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500452 - V425,2.00,NPT,CI,NO/LS/SAO/BL

$477.06$578.42

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500456 - V426,2.00,BSP,CI,NO,FLT/3000,

$1,191.19$1,444.28

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500463 - V424,1.50,NPT,CI,NC,

$337.35$409.02

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500464 - V421,.75,NPT,CI,NO,3010FLT,54

$918.27$1,113.37

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500465 - V424,1.50,NPT,CI,NO,DT#1,BLU

$263.65$319.66

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500477 - V421,1.00,NPT,CI,NC/LS,BL

$243.89$295.71

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500483 - V421,1.00,NPT,CI,NO/PI/SAO,BL

$276.40$335.12

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500488 - VAV8,4.00,ASTM,CI,NC

$1,515.39$1,837.36

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500489 - V428,4.00,ISO,CI,NC/LS

$1,452.53$1,761.15

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500491 - V427,3.00,ISO,CI,NO/LS,FKM

$990.48$1,200.93

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500493 - V427,3.00,NPT,CI,NO/LS,

$862.41$1,045.64

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500422 - V421,1.00,NPT,CI,NC,BLUE

$214.48$260.05

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500423 - K535,2.00,PLS,XNC/LS/PI/SAC

$1,044.77$1,266.75

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500424 - K535,2.00,PLS,NO/SC100 DT 1,

$1,532.70$1,858.35

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500425 - V461,1.00,NPT,SS,NO/SAO,BUNA

$601.99$729.89

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500426 - V427,3.00,NPT,CI,NC,

$695.10$842.78

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500438 - V424,1.25,NPT,CI,NC/SAC,

$335.42$406.68

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500439 - K535,2.00,PLS,NO, DT BOSS #1

$843.26$1,022.43

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500440 - V428,4.00,ASTM,CI,NO/LS/SAO,B

$1,439.66$1,745.54

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500441 - V428,4.00,ASTM,CI,NC/LS,BLUE

$1,452.53$1,761.15

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500443 - K531,1.00,PLS,NO,EO,STD,DT #

$611.30$741.18

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500445 - V424,1.50,NPT,CI,NC/LS,

$308.08$373.53

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500446 - V424,1.50,NPT,CI,NO/PI/SAO

$400.24$485.28

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500447 - V426,2.50,NPT,CI,NC,HI TEMP,E

$500.40$606.72

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500452 - V425,2.00,NPT,CI,NO/LS/SAO/BL

$477.06$578.42

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500456 - V426,2.00,BSP,CI,NO,FLT/3000,

$1,191.19$1,444.28

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500463 - V424,1.50,NPT,CI,NC,

$337.35$409.02

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500464 - V421,.75,NPT,CI,NO,3010FLT,54

$918.27$1,113.37

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500465 - V424,1.50,NPT,CI,NO,DT#1,BLU

$263.65$319.66

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500477 - V421,1.00,NPT,CI,NC/LS,BL

$243.89$295.71

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500483 - V421,1.00,NPT,CI,NO/PI/SAO,BL

$276.40$335.12

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500488 - VAV8,4.00,ASTM,CI,NC

$1,515.39$1,837.36

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500489 - V428,4.00,ISO,CI,NC/LS

$1,452.53$1,761.15

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500491 - V427,3.00,ISO,CI,NO/LS,FKM

$990.48$1,200.93

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4500493 - V427,3.00,NPT,CI,NO/LS,

$862.41$1,045.64

You save 18%
Should ship between 17 Nov and 01 Dec

Subject to factory lead times

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