Diaphragm Valves

Diaphragm valves are designed to regulate the flow of liquids and gases by using a flexible diaphragm to create a secure seal. These valves are ideal for applications where the transported media is corrosive, abrasive, or requires sanitary handling. Their simple yet effective design minimizes the risk of contamination, making them widely used in industries such as chemical processing, pharmaceuticals, food and beverage, and water treatment.


Centro offers a comprehensive selection of diaphragm valves in manual and pneumatic actuated designs to suit various operational needs. Whether you require precise hand-operated flow control or an automated valve for high-efficiency processing, we have the right solution.

Types of Diaphragm Valves We Offer

  • Manual Diaphragm Valves – Hand-operated for precise control in low-pressure systems
  • Pneumatic Actuated Diaphragm Valves – Use compressed air for automated on/off operation
  • Weir-Type Diaphragm Valves – Provide excellent sealing for corrosive and particulate-laden fluids
  • Straight-Through Diaphragm Valves – Offer minimal flow resistance for high-purity applications
  • Sanitary Diaphragm Valves – Designed for hygienic industries, including food, beverage, and pharmaceuticals

Why Choose Diaphragm Valves from Centro?

  • Superior sealing performance for corrosive, abrasive, and sanitary applications
  • Available in a variety of materials, including stainless steel, plastic, and lined options
  • Suitable for industries such as chemical processing, pharmaceuticals, biotechnology, and water treatment
  • Sourced from trusted manufacturers to ensure durability, reliability, and compliance with industry standards


Centro provides high-quality diaphragm valves designed for long-lasting performance. Browse our selection and order online today, or contact our team for expert assistance in selecting the right valve for your application.

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AQ Matic/Aquamatic and Control Valves 4510425 - V421,0.75,NPT,CI,NO/PI/SAO

$332.40$403.02

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510428 - K526,2.50,PLS,NC

$764.88$927.39

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510429 - K531,1.00,PLS,LS/PI/SAC,EO,

$704.19$853.81

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510430 - K534,1.50,PLS,NO/SC60

$972.50$1,179.13

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510431 - V421,0.75,NPT,CI,NO/SAC,BLUE

$237.34$287.76

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510432 - V461,1.00,ASTM,SS,NC/SAC,BUNA

$676.72$820.50

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510433 - K524,1.50,PLS,NO/LS/SAC,EC

$610.86$740.64

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

The AQ Matic V42 Series Y-pattern diaphragm valves are engineered for rugged, high-performance service in both air and liquid systems. The V42‑5 variant delivers a 2″ NPT connection, a cast iron body, normally-open action, energize-to-open solenoid, and dry-drain capability, ideal for dew-point control, compressed air sequencing, and high-cycle actuation systems. These valves are proudly manufactured in the USA with global components for long life and reliability.

$707.76$858.14

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510438 - K524,1.50,PLS,NO/PI/SAO

$373.79$453.21

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510444 - V424,1.25,NPT,CI,NO/SAC

$542.31$657.53

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510445 - K524,1.50,PLS,NO/SAO,DTB

$280.01$339.50

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510446 - V426,2.00,NPT,CI,NO/SAC

$627.11$760.35

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510447 - V427,3.00,NPT,CI,NO,DT #2,BL

$662.82$803.64

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510449 - K526,2.50,PLS,NO/PI/SAO

$797.47$966.91

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510455 - V427,3.00,ASTM,CI,NO,PAINT BL

$814.45$987.49

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510456 - V428,4.00,ASTM,CI,NO/LS

$1,628.81$1,974.88

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510462 - V428,4.00,ASTM.CI,NO/LS

$1,422.99$1,725.33

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510464 - V428,4.00,ASTM.CI,SAC,EO

$1,756.72$2,129.97

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510465 - V428,4.00,ASTM.CI,SAC,EC

$1,756.72$2,129.97

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510466 - K534,1.50,PLS,NO,EO,120V

$761.42$923.20

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510467 - V427,3.00,NPT,CI,NO/LS,

$730.04$885.15

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510468 - V427,3.00,NPT,CI,NO/LS,

$730.04$885.15

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510471 - V428,4.00,ISO,CI,NO,EC

$1,585.53$1,922.41

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510479 - V424,1.50,NPT,CI,NO,VITON,HI

$310.47$376.43

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510425 - V421,0.75,NPT,CI,NO/PI/SAO

$332.40$403.02

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510428 - K526,2.50,PLS,NC

$764.88$927.39

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510429 - K531,1.00,PLS,LS/PI/SAC,EO,

$704.19$853.81

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510430 - K534,1.50,PLS,NO/SC60

$972.50$1,179.13

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510431 - V421,0.75,NPT,CI,NO/SAC,BLUE

$237.34$287.76

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510432 - V461,1.00,ASTM,SS,NC/SAC,BUNA

$676.72$820.50

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510433 - K524,1.50,PLS,NO/LS/SAC,EC

$610.86$740.64

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

The AQ Matic V42 Series Y-pattern diaphragm valves are engineered for rugged, high-performance service in both air and liquid systems. The V42‑5 variant delivers a 2″ NPT connection, a cast iron body, normally-open action, energize-to-open solenoid, and dry-drain capability, ideal for dew-point control, compressed air sequencing, and high-cycle actuation systems. These valves are proudly manufactured in the USA with global components for long life and reliability.

$707.76$858.14

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510438 - K524,1.50,PLS,NO/PI/SAO

$373.79$453.21

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510444 - V424,1.25,NPT,CI,NO/SAC

$542.31$657.53

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510445 - K524,1.50,PLS,NO/SAO,DTB

$280.01$339.50

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510446 - V426,2.00,NPT,CI,NO/SAC

$627.11$760.35

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510447 - V427,3.00,NPT,CI,NO,DT #2,BL

$662.82$803.64

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510449 - K526,2.50,PLS,NO/PI/SAO

$797.47$966.91

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510455 - V427,3.00,ASTM,CI,NO,PAINT BL

$814.45$987.49

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510456 - V428,4.00,ASTM,CI,NO/LS

$1,628.81$1,974.88

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510462 - V428,4.00,ASTM.CI,NO/LS

$1,422.99$1,725.33

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510464 - V428,4.00,ASTM.CI,SAC,EO

$1,756.72$2,129.97

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510465 - V428,4.00,ASTM.CI,SAC,EC

$1,756.72$2,129.97

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510466 - K534,1.50,PLS,NO,EO,120V

$761.42$923.20

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510467 - V427,3.00,NPT,CI,NO/LS,

$730.04$885.15

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510468 - V427,3.00,NPT,CI,NO/LS,

$730.04$885.15

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510471 - V428,4.00,ISO,CI,NO,EC

$1,585.53$1,922.41

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

AQ Matic/Aquamatic and Control Valves 4510479 - V424,1.50,NPT,CI,NO,VITON,HI

$310.47$376.43

You save 18%
Should ship between 16 Nov and 30 Nov

Subject to factory lead times

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